History of Reoviridae
1943
1944
1973
1974
1981
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1943 - Jacob Light and Horace Hodes isolate an infectious, filtrable agent associated with diarrheal disease
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1944 - Colorado Tick Fever Virus is first isolated from human blood
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1973 - Bishop, Davidson, Holmes, and Ruck find Rotavirus in the cytoplasm of duodenal epithelial cells and feces
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1974 - Thomas Flewett proposes the name rotavirus after noticing a wheel-like resemblence under a microscope
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1981 - Trypsin, a protease involved in digestion, is associated with rotaviral replication
1998
1999
2006
2008
2015
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1998 - Rotashield, the first vaccine against rotavirus, is licensed and recommended
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1999 - Wyeth Pharmaceuticals withdraw Rotashield after alegations are made associating the vaccine with intussusception
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2006 - Rotateq, a new vaccine against rotavirus, becomes available
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2008 - Rotarix, another vaccine against rotavirus, becomes available.
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2015 - Bharat Biotech announces a $1 rotavirus vaccine (Rotavac) to be made available in India